Contraceptif féminin non hormonal

Non-hormonal female contraceptive

Abstract

La présente invention concerne des compositions et des procédés permettant de réguler la fertilité d'un sujet féminin. Plus particulièrement, l'invention porte, à titre d'exemple, sur des compositions comprenant des dérivés de sucre, tels que le 2-désoxyglucose, le D-mannoheptulose, et/ou le 5-thio-D-glucose. L'invention porte en outre sur des procédés de préservation de la production d'ovules chez un sujet féminin, impliquant l'administration de dérivés de glucose. La composition comprend, en règle générale, un dérivé de glucose qui influence l'expression de Foxo3a.
Disclosed herein are compositions and methods for controlling fertility of a female subject. Particularly exemplified are compositions comprising sugar derivatives, such as 2-deoxyglucose, D-mannoheptulose; and/or 5-thio-D-glucose. Also disclosed herein are methods of preserving ova supply in a female subject that involves administering glucose derivatives. The composition typically includes a glucose derivative that affects Foxo3a expression.

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Patent Citations (3)

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    US-6110471-AAugust 29, 2000The Board Of Trustees Of The Leland Stanford Junior UniversityNon-hormonal method of contraception
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NO-Patent Citations (1)

    Title
    LOBL, T. J. ET AL.: 'ANTIFERTILITY ACTIVITIES OF 5-THIO-D-GLUCOSE IN MICE AND RATS' CONTRACEPTION vol. 17, no. 2, February 1978, pages 123 - 130

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    Publication numberPublication dateAssigneeTitle